The hygiene hypothesis has been a sexy but controversial topic in all the health sciences since its conception in the late 1980’s. The hypothesis being that developed countries have higher incidences of allergy because they are generally cleaner. Sounds simple but 20+ years later, it’s one of the most debated theories in the field. It started with an observation by David Strachan that, in a longitudinal study of individuals from birth to age 23, the incidence of hay fever was inversely correlated with the number of children in the household. In other words, the kids that got hay fever, which...
23andMe allergy antibiotics app apps Buzzwords cancer career causation cognitive bias correlation CRISPR DNA epigenetics Events functional genomics genes Genetics genetic testing GWAS history of science Immunology interview journal lab notebook leadership logical fallacy manuscript mentorship microbiome mucosal Mutant Mutations negative results optimization podcast publication reproducibility Research Science policy scientific method soft skills success technology tolerance